Salicylic Acid Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD (2024)

This medication is for use on the skin only. For best results, soak the skin area in warm water for at least 5 minutes before using this medication. After soaking, gently wipe off any loose skin with a clean, soft cloth. Do not rub. Apply a thin film of medication to the affected area as directed by your doctor, usually once daily at bedtime. Cover the area loosely if directed by your doctor. When you wake up, gently wash off the medication. Wash hands after use, unless you are using this medication to treat the hands.

If you are using the foam, shake the can well before using. Before using a new can, prime the container by pressing down for 3 to 5 seconds until foam appears. Spray the foam onto the hand, then apply. After applying the foam, gently rub it in until it disappears.

Moisture is very important to help the medication work, so your doctor may direct you to cover the treated area to help hold moisture next to the skin. Do not cover the area with ointment, plastic/waterproof bandages, tight-fitting clothing, or tight dressings unless directed by your doctor. Doing so may increase side effects. If you are treating an area that is difficult to cover, your doctor may direct you to moisten the skin with wet packs or baths or to use the medication more often. Use exactly as prescribed.

This medication may be used on the body, the scalp, the palms of the hands, and the soles of the feet. Avoid your eyes, nostrils, mouth, and genitals. If contact occurs, flush the area with cool water for 15 minutes. Be careful when applying this medication because it can irritate normal skin around the treated area.

Do not use large amounts, apply it more often, or use it for a longer time than directed. Your condition will not clear faster, but the chance for side effects may be increased.

You will usually see some improvement in 2 to 3 days, but it may take longer to get the full benefit. Once your skin has improved, your doctor may direct you to use this product only occasionally or to stop using it. Tell your doctor if your condition lasts or gets worse.

Salicylic Acid Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD (2024)

FAQs

What is the main side effect of salicylic acid? ›

Slight burning, skin redness, and peeling may occur. These effects are expected. If any of these effects worsen, tell your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects.

Why is salicylic acid bad for skin? ›

Although salicylic acid is considered safe overall, it may cause skin irritation when first starting. It may also remove too much oil, resulting in dryness and potential irritation. Other potential side effects include : skin tingling or stinging.

What are the warnings of salicylic acid? ›

Incidence not known
  • Difficult breathing.
  • dryness and peeling of skin.
  • fainting.
  • hives or itching.
  • redness of the skin.
  • swelling of the eyes, face, lips, or tongue.
  • tightness in the throat.
  • unusually warm skin.
Apr 1, 2024

When should you not use salicylic acid? ›

Also, do not use this medicine if you are a diabetic or if you have poor blood circulation. Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.

Is it bad to use salicylic acid on your face everyday? ›

"If salicylic acid is an ingredient in your cleanser, it is fine to use it every day." However, if you are using an exfoliant that has salicylic acid in the formula, Dr. Hu advised only using the product three times per week to avoid over-exfoliating the skin and drying it out.

What are the main hazards for salicylic acid? ›

The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system and acid-base balance in the body. This may result in delirium and tremors.

What happens if you use too much salicylic acid on skin? ›

Skin reactions such as peeling/burning/dry/reddened skin may occur, especially at the start of treatment. If any of these effects last or get worse, tell your doctor or pharmacist promptly. You may need to apply smaller amounts of the drug or use it less often.

Why is my skin getting worse after using salicylic acid? ›

1 Known as "skin purging," worsening acne is a short-term reaction to ingredients that speed up cell turnover. Salicylic acid helps your body quickly get rid of dead skin cells. As a result, those dead skin cells, dirt, and oils appear on the surface of your skin, which clogs your pores and causes acne.

Is salicylic acid good for mature skin? ›

Salicylic acid is a popular skin care ingredient found in many over-the-counter products. It offers various benefits for the skin. It is commonly used to treat acne, blackheads, warts, corns, psoriasis, and signs of aging.

Who Cannot use salicylic acid? ›

Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in children. Use of salicylic acid topical in children younger than 2 years of age is not recommended.

Does salicylic acid get into bloodstream? ›

People who use this drug for a long time or over large areas of skin may rarely have serious side effects caused by this drug entering the bloodstream. Children younger than 12 years and people with liver or kidney problems are more at risk.

How toxic is salicylic acid? ›

A dose of greater than 500 mg/kg of salicylate can result in severe hyperpnea, coma, and occasionally seizures. About 20% of the salicylate is oxidized in the tissues and 70% is excreted by the kidneys.

What medications interact with salicylic acid? ›

Medications known to interact with salicylic acid topical
  • adapalene topical.
  • alitretinoin topical.
  • bexarotene topical.
  • clascoterone topical.
  • isotretinoin.
  • tazarotene topical.
  • tretinoin topical.
  • trifarotene topical.

What can you not mix with salicylic acid? ›

Ingredients to Never Mix With Salicylic Acid
  • Glycolic Acid. ...
  • Benzoyl Peroxide.
Jan 2, 2023

Is salicylic acid bad for the liver? ›

Salicylic acid is a widely used nonsteroidal anti-inflammatory drug (NSAID). But it is known to cause serious liver damage occasionally. Mitochondrial dysfunction and oxidative stress are predicted to be the major factors of salicylic acid-induced liver injury.

What happens to your skin when you start using salicylic acid? ›

As Salicylic acid is speeding up the rate at which your skin evicts old skin cells, it can sometimes initially cause more breakouts to come to the surface. This process is also known as purging. These blemishes were lurking there anyway, but have just made a more prompt appearance.

What happens if you use too much salicylic acid? ›

There can always be too much of a good thing and salicylic acid is no different. The main negative side effect when overused is it can irritate and cause excess dryness. If you have sensitive skin, choose your formula carefully as some products contain denatured alcohol, which can be additionally drying.

What is the toxicity of salicylic acid? ›

Nausea, vomiting, diaphoresis, and tinnitus are the earliest signs and symptoms of salicylate toxicity. Other early symptoms and signs are vertigo, hyperventilation, tachycardia, and hyperactivity. As toxicity progresses, agitation, delirium, hallucinations, convulsions, lethargy, and stupor may occur.

Can salicylic acid damage the skin barrier? ›

Also, avoid using cleansers and toners containing AHAs or BHAs like glycolic acid or salicylic acid. Using all of these too often or incorrectly is probably the reason why your skin barrier is damaged. When your skin barrier is compromised, it's time to cut back on complex skincare and allow it just be.

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